The issue continues on my iPad Air and my wife's mini 2, I don't use Safari very often with my iPhone so have not followed the problem there. My initial contact with Apple Support took me to a tech who had not hear of the problem. But before we concluded our discussion my portable land line phone gave out (have now replaced it with new one) and I have not initiated another contact with Support.
However, two other Vmug members have advised me that they have had the same experience.
What appears to happen is this, for example:
In Mail I receive a C/net newsletter listing articles with a brief synopsis, I tap the item for more detail and Safari opens, but not to the article web site but rather to my icon list of Favorites. I tap left right top to return to Mail and tap the same article and now Safari opens cnet.com and the article. Should I decide to open another article from C/net, no problem. I now return to Mail and decide to brows another source, The Guardian, The Intercept, Foreign Affairs, etc and select links to the Web and generally no problem.
However, if I shut down my iPad or allow it to go to sleep then return to it later and log in the first attempt to link to the Web opens Safari to my Favorites.
My solution would be to make another browser the default, but from what I read on the net suggest it is possible but beyond my technical abilities.
I guess I could uninstall iOS 10.0.2 and reinstall but this is not something that I am comfortable with doing.
The issue is not a big deal but rather a pain in the ___
Dan Horovatin